Publications
2021 – 2023
Long, K. R., Rbaibi, Y., Kashlan, O. B., & Weisz, O. A. (2023). Receptor-associated protein impairs ligand binding to megalin and megalin-dependent endocytic flux in proximal tubule cells. American journal of physiology. Renal physiology, 325(4), F457–F464. https://doi.org/10.1152/ajprenal.00165.2023 PDF
Rbaibi, Y., Long, K. R., Shipman, K. E., Ren, Q., Baty, C. J., Kashlan, O. B., & Weisz, O. A. (2023). Megalin, cubilin, and Dab2 drive endocytic flux in kidney proximal tubule cells. Molecular biology of the cell, 34(7), ar74. https://doi.org/10.1091/mbc.E22-11-0510 PDF
Shipman, K. E., Baty, C. J., Long, K. R., Rbaibi, Y., Cowan, I. A., Gerges, M., Marciszyn, A. L., Kashlan, O. B., Tan, R. J., Edwards, A., & Weisz, O. A. (2023). Impaired Endosome Maturation Mediates Tubular Proteinuria in Dent Disease Cell Culture and Mouse Models. Journal of the American Society of Nephrology : JASN, 34(4), 619–640. https://doi.org/10.1681/ASN.0000000000000084 PDF
Shipman, K. E., Long, K. R., Cowan, I. A., Rbaibi, Y., Baty, C. J., & Weisz, O. A. (2022). An Adaptable Physiological Model of Endocytic Megalin Trafficking in Opossum Kidney Cells and Mouse Kidney Proximal Tubule. Function (Oxford, England), 3(6), zqac046. https://doi.org/10.1093/function/zqac046 PDF
Rinschen, M. M., Palygin, O., El-Meanawy, A., Domingo-Almenara, X., Palermo, A., Dissanayake, L. V., Golosova, D., Schafroth, M. A., Guijas, C., Demir, F., Jaegers, J., Gliozzi, M. L., Xue, J., Hoehne, M., Benzing, T., Kok, B. P., Saez, E., Bleich, M., Himmerkus, N., Weisz, O. A., … Staruschenko, A. (2022). Accelerated lysine metabolism conveys kidney protection in salt-sensitive hypertension. Nature communications, 13(1), 4099. https://doi.org/10.1038/s41467-022-31670-0 PDF
Long, K. R., Rbaibi, Y., Bondi, C. D., Ford, B. R., Poholek, A. C., Boyd-Shiwarski, C. R., Tan, R. J., Locker, J. D., & Weisz, O. A. (2022). Cubilin-, megalin-, and Dab2-dependent transcription revealed by CRISPR/Cas9 knockout in kidney proximal tubule cells. American journal of physiology. Renal physiology, 322(1), F14–F26. https://doi.org/10.1152/ajprenal.00259.2021 PDF
AJP Renal_Cover_April – June 2022_high-rez PDF
Edwards, A., Long, K. R., Baty, C. J., Shipman, K. E., & Weisz, O. A. (2022). Modelling normal and nephrotic axial uptake of albumin and other filtered proteins along the proximal tubule. The Journal of physiology, 600(8), 1933–1952. https://doi.org/10.1113/JP282885 PDF
Weisz O. A. (2021). Considerations in Comparing Proximal Tubule Cell Culture Models. Journal of the American Society of Nephrology : JASN, 32(8), 2099–2100. https://doi.org/10.1681/ASN.2021040510 PDF
Weisz O. A. (2021). Endocytic adaptation to functional demand by the kidney proximal tubule. The Journal of physiology, 599(14), 3437–3446. https://doi.org/10.1113/JP281599 PDF
2020 – 2016
Park HJ, Fan Z, Bai Y, Ren Q, Rbaibi Y, Long KR, Gliozzi ML, Rittenhouse N, Locker JD, Poholek AC, and Weisz OA (2020). Transcriptional programs driving shear stress-induced differentiation of kidney proximal tubule cells in culture. Frontiers in Physiol. 11:587358. DOI: 10.3389/fphys.2020.587358. PDF
Ren Q, Weyer K, Rbaibi Y, Long KR, Tan RJ, Nielsen R, Christensen EI, Baty CJ, Kashlan OB, and Weisz OA (2020) Distinct functions of megalin and cubilin receptors in recovery of normal and nephrotic levels of filtered albumin. Am J Physiol- Renal Physiol. 318:F1284-1294. doi: 10.1152/ajprenal.00030.2020. PMID: 32200668 PDF
Long KR, Rbaibi Y, Gliozzi ML, and Weisz OA (2020) Differential kidney proximal tubule cell responses to protein overload by albumin and its ligands. Am J Physiol- Renal Physiol. 318:F851–F859. doi:10.1152/ajprenal.00490.2019. PMID: 32068462 PDF
Gliozzi ML, Espiritu E, Shipman KE, Rbaibi Y, Long KR, Roy N, Duncan AW, Lazzara MJ, Hukriede NA, Baty CJ, and Weisz OA (2020) Effects of proximal tubule shortening on protein excretion in a Lowe Syndrome model. J Am Soc Nephrol. 31:67-83.doi: link. PDF Suppl. Data
Gliozzi ML, Rbaibi Y, Long KR, Vitturi DA, and Weisz OA (2019) Hemoglobin alters vitamin carrier uptake and vitamin D metabolism in proximal tubule cells: implications for sickle cell disease. Am J Physiol- Cell Physiol. 317:C993-C1000. doi: 10.1152/ajpcell.00287.2019. PMID: 31509446; PMCID: PMC6879883. PDF
Ren Q, Gliozzi ML, Rittenhouse NL, Edmunds LR, Rbaibi Y, Locker JD, Poholek AC, Jurczak MJ, Baty CJ, and Weisz OA (2019) Shear stress and oxygen availability drive differential changes in OK proximal tubule cell metabolism and endocytosis. Traffic. 20:448-459. doi: 10.1111/tra.12648. PMCID: PMC7055529. PDF
Tomich AD, Klontz EH, Deredge D, Barnard JP, McElheny CL, Eshbach ML, Weisz OA, Patrick Wintrode P, Doi Y, Sundberg EJ and Sluis-Cremer N (2019) Small molecule inhibitor of FosA expands fosfomycin activity to multidrug-resistant Gram-negative pathogens. Antimicrobial Agents and Chemotherapy. 63:e01524-18. doi: 10.1128/AAC.01524-18. PMID: 30642934 PDF
Bhattacharyya S, Jean-Alphonse F, Raghavan V, Vilardaga J-P, Carattino MD, and Weisz OA (2017) Cdc42 couples fluid shear stress to apical endocytosis in proximal tubule cells. Physiol Rep. 2017 Oct;5(19):e13460. doi: 10.14814/phy2.13460. PMID: 29038362; PMCID: PMC5641940. PDF
Long KR, Shipman KE, Rbaibi Y, Menshikova E, Ritov VB, Eshbach ML, Jiang Y, Jackson EK, Baty CJ, and Weisz OA (2017) Proximal tubule apical endocytosis is modulated by fluid shear stress via an mTOR-dependent pathway. Mol Biol Cell. 28:2508-2517. (highlighted by the Faculty of 1000). PMID: 28720662; PMCID: PMC5597323. PDF
Eshbach ML, Sethi R, Avula R, Lamb J, Hollingshead DJ, Finegold DN, Locker J, Chandran UR, and Weisz OA (2017) The transcriptome of the Didelphis virginiana opossum kidney OK proximal tubule cell line. Am J Physiol- Renal Physiol. 313:F585-F595. PMID: 28356267; PMCID: PMC5494590. PDF
Eshbach ML, Kaur A, Rbaibi Y, Tejero J, and Weisz OA (2017) Hemoglobin inhibits albumin uptake by proximal tubule cells: implications for sickle cell disease. Am J Physiol- Cell Physiol. 312:C733-C740. (featured as “Image of the Week” for AJP-Cell Physiology Social Media; highlighted in APSselect) PMID: 28615248; PMCID: PMC5494590. PDF
Pereira EM, Labilloy A, Eshbach ML, Roy A, Subramanya AR, Monte S, Labilloy G, and Weisz OA (2016) Characterization and phosphoproteomic analysis of a human immortalized podocyte model of Fabry disease generated using CRISPR/Cas9 technology. Am J Physiol- Renal Physiol. 311:F1015-F1024. PMID: 27681560; PMCID: PMC5130460. PDF
Sneddon WB, Ruiz GW, Gallo LI, Xiao K, Zhang Q, Rbaibi Y, Weisz OA, Apodaca GL, and Friedman PA (2016) Convergent signaling pathways regulate parathyroid hormone and fibroblast growth factor-23 action on NPT2A-mediated phosphate transport. J Biol Chem, 291:18632-18642. PMID: 27432882; PMCID: PMC5009241 PDF
2015 – 2011
Raghavan V, Rbaibi R, Pastor-Soler N, Carattino MD, and Weisz OA (2014) Shear stress dependent regulation of apical endocytosis in renal proximal tubule cells mediated by primary cilia. Proc Natl Acad Sci USA.111:8506-8511. PMCID: 4060694. PDF
Szalinski CM, Labilloy A, Bruns JR, and Weisz OA (2014) VAMP7 modulates ciliary biogenesis in renal epithelial cells. PLoS One. 9:e86425. PMCID: 3899255. PDF
Mattila PE, Raghavan V, Rbaibi Y, Baty CJ, and Weisz OA (2014) Rab11a-positive compartments in proximal tubule cells sort fluid phase and membrane cargo. Am J Physiol- Cell Physiol. 306:C441-449. (featured as an Editorial Focus 306:C428-430). PMCID: 4042618. PDF
Labilloy A, Youker RT, Bruns JR, Kukic I, Kiselyov K, Halfter W, Finegold D, do Monte SJ, and Weisz OA (2014) Altered dynamics of a lipid raft associated protein in a kidney model of Fabry disease. Mol Genet Metab. 111:184-192. PMCID: 3946758. PDF
Razawi H, Kinlough CL, Staubach S, Poland PA, Rbaibi Y, Weisz OA, Hughey RP, and Hanisch, FG (2013) Evidence for core 2 to core 1 O-glycan remodeling during recycling of MUC1. Glycobiology. 23:935-945. PMCID: 3695752. PDF
Youker RT, Bruns JR, Costa SA, Rbaibi Y, Lanni F, Kashlan OB, Teng H, and Weisz OA (2013) Multiple motifs regulate apical sorting of p75 via a mechanism that involves dimerization and higher-order oligomerization. Mol Biol Cell. 24:1996-2007. PMCID: 3681702. PDF
Szalinski CM, Guerriero CJ, Ruiz WG, Docter BE, Rbaibi Y, Pastor-Soler N, Apodaca G, Puthenveedu MA, and Weisz OA (2013) PIP5KIb selectively modulates apical endocytosis in polarized renal epithelial cells. PLoS One. 8:e53790. PMCID: 3547069. PDF
Mo D, Ihrke G, Costa SA, Brilli L, Labilloy A, Halfter W, Cianciolo Cosentino C, Hukriede NA, and Weisz OA (2013) Apical targeting and endocytosis of the sialomucin endolyn are essential for establishment of zebrafish pronephric kidney function. J Cell Sci. 125: 5546-5554 (highlighted by the Faculty of 1000). PMCID: 3561862. PDF
Mo D, Costa SA, Ihrke G, Youker RT, Pastor-Soler N, Hughey RP, and Weisz OA (2012) Sialylation of N-linked glycans mediates apical delivery of endolyn in MDCK cells via a galectin-9 dependent mechanism. Mol Biol Cell. 23:3636-3646 (highlighted in Mol Biol Cell). PMCID: 3442411. PDF
Rbaibi Y, Cui S, Mo D, Carattino M, Rohatgi, R, Satlin LM, Szalinski CM, Swanhart LM, Fölsch H, Hukriede NA, and Weisz OA (2012) OCRL1 modulates cilia length in renal epithelial cells. Traffic. 13:1295-1305. PMCID: 3652247. PDF
Colletti GA, Miedel MT, Quinn J, Andharia N, Weisz OA, and Kiselyov K (2012). Loss of the lysosomal ion channel TRPML1 leads to cathepsin B-dependent apoptosis. J Biol Chem. 287:8082-8091. PMCID: 3318733. PDF
Mattila PE, Youker RT, Mo D, Bruns JR, Cresawn KO, Hughey RP, Ihrke G, and Weisz OA (2012) Multiple biosynthetic trafficking routes for apically secreted proteins in MDCK cells. Traffic. 13:433-442. PMCID: 3276681. PDF
Kinlough CL, Poland PA, Gendler SJ, Mattila PE, Mo D, Weisz OA, and Hughey RP (2011) Core-glycosylated mucin-like repeats from MUC1 are an apical targeting signal. J Biol Chem. 286:39072-39081 (highlighted by the Faculty of 1000). PMCID: 3234732. PDF
Rondanino C Poland PA, Kinlough CL, Li H, Rbaibi Y, Myerburg MM, Al-bataineh M, Kashlan OB, Pastor-Soler N, Hallows KR, Weisz OA, Apodaca G, and Hughey RP (2011) Galectin-7 modulates the length of the primary cilia and wound repair in polarized kidney epithelial cells. Am J Physiol- Renal Physiol. 301:F622-633. PMCID: 3174547. PDF
2010 – 2006
Mo D, Potter BA, Bertrand CA, Hildebrand JD, Bruns JR, and Weisz OA (2010) Nucleofection disrupts tight junction fence function to alter membrane polarity of renal epithelial cells. Am J Physiol- Renal Physiol. 299:F1178-F1184. PMCID: 2980404. PDF
Cui S, Guerriero CJ, Szalinski CM, Kinlough CL, Hughey RP, and Weisz OA (2010) OCRL1 function in renal epithelial membrane traffic. Am J Physiol- Renal Physiol. 298: F335-F345. PMCID: 2822509. PDF
Jin J, Sturgeon T, Weisz OA, Mothes W, and Montelaro RC (2009) HIV-1 matrix dependent membrane targeting is regulated by Gag mRNA trafficking. PLoS One. 4; e6551. PMCID: 2717210. PDF
Mattila PE, Kinlough CL, Bruns JR, Weisz OA, and Hughey RP (2009) MUC1 traverses apical recycling endosomes along the biosynthetic pathway in polarized MDCK cells. Biol Chem. 2009; 390; 551-556. PMCID: 3625034. PDF
Khandelwal P, Ruiz WG, Balestreire-Hawryluk E, Weisz OA, Goldenring JR, and Apodaca G (2008) Rab11a-dependent exocytosis of discoidal/fusiform vesicles in bladder umbrella cells. Proc Natl Acad Sci USA. 105:15773-15778. PMCID: 2572972. PDF Suppl.
Leaphart CL, Dai S, Gribar SC, Richardson W, Ozolek J, Shi X, Bruns JR, Branca M, Li J, Weisz OA, Sodhi C, and Hackam DJ (2008) Interferon-gamma inhibits enterocyte migration by reversibly displacing connexin43 from lipid rafts. Am J Physiol-Gastroint and Liver Physiol. 295:G259-G269. PMCID: 2536784. PDF
Guerriero CJ, Lai Y, and Weisz OA (2008) Differential sorting and Golgi export requirements for raft-associated and raft-independent apical proteins along the biosynthetic pathway. J Biol Chem. 283:18040-18047. PMCID: 2440606. PDF
Miedel MT, Rbaibi Y, Guerriero CJ, Colletti G, Weixel KM, Weisz OA* and Kiselyov K* (2008) Membrane traffic and turnover in TRP-ML1 deficient cells: A revised model for Mucolipidosis Type IV pathogenesis, J Exp Med. 205:1477-1490 *corresponding authors (Cover article; highlighted in the In This Issue section of Journal of Experimental Medicine 2008; 205:1247). PMCID: 2413042. PDF
Weixel KM, Edinger RS, Kester L, Guerriero CJ, Wang H, Fang L, Kleyman TR, Welling PA, Weisz OA, and Johnson JP (2007) Phosphatidylinositol 4-phosphate 5-kinase reduces cell surface expression of the epithelial sodium channel (ENaC) in cultured collecting duct cells. J Biol Chem. 282:36534-36542. PDF
Oztan A, Silvis M, Weisz OA, Bradbury NA, Hsu S-C, Goldenring JR, Yeaman C, and Apodaca G. (2007) Exocyst requirement for endocytic traffic directed toward the apical and basolateral poles of polarized MDCK cells. Mol Biol Cell. 18:3978-3992. PMCID: 1995710. PDF
Cresawn KO, Potter BA, Oztan A, Guerriero CJ, Ihrke G, Goldenring JR, Apodaca G, and Weisz OA (2007) Differential involvement of endocytic compartments in the biosynthetic traffic of apical proteins. EMBO J. 26:3737-3748 (highlighted by the Faculty of 1000). PMCID: 1952228. PDF Suppl. Suppl. Refs.
Jin J, Sturgeon T, Chen C, Watkins SC, Weisz OA, and Montelaro RC (2007) Distinct intracellular trafficking of EIAV and HIV-1 Gag during viral assembly and budding revealed by bimolecular fluorescence complementation assays. J Virol. 81:11226-11235. PMCID: 2045577. PDF
Chen C, Jing J, Rubin M, Huang L, Sturgeon T, Weixel KM, Stolz DB, Watkins SC, Bamburg JR, Weisz OA, and Montelaro RC (2007) Association of Gag multimers with filamentous actin during equine infectious anemia virus assembly. Curr HIV Res. 5:315-323.
Bruns JB, Carattino MD, Sheng S, Maarouf AB, Weisz OA, Pilewski JM, Hughey RP, and Kleyman TR (2007) Epithelial Na+ channels are fully activated by furin- and prostasin-dependent release of an inhibitory peptide from the gamma subunit. J Biol Chem. 282:6153-6160. PDF
Guerriero CJ and Weisz OA (2007) The N-WASP inhibitor wiskostatin non-selectively perturbs membrane transport by decreasing cellular ATP levels Am J Physiol- Cell Physiol. 292:C1562-1566. PDF
Lu C, Walker WH, Sun J, Weisz OA, Gibbs RB, Witchel SF, Sperling MA, and Menon RK (2006) Insulin-like peptide 6 (Insl6): Characterization of secretory status and post-translational modifications. Endocrinology. 147:5611-5623. PDF
Blumental-Perry A, Haney CJ, Weixel KM, Watkins SC, Weisz OA, and Aridor M (2006) Phosphatidylinositol 4-phosphate formation at ER exit sites regulates ER export. Dev Cell. 11:671-682 (highlighted by the Faculty of 1000). PDF
Ellis MA, and Weisz OA (2006) In vitro assays differentially recapitulate protein export from the trans-Golgi network. Anal Biochem. 354:314-315. PDF
Guerriero CJ, Weixel KM, Bruns JR, and Weisz OA (2006) Phosphatidylinositol 5-kinase stimulates apical biosynthetic delivery via an Arp2/3-dependent mechanism. J Biol Chem. 281:15376-15384. PDF
Miedel MT, Weixel KM, Bruns JR, Traub LM, and Weisz OA (2006) Posttranslational cleavage and adaptor protein complex-dependent trafficking of mucolipin-1. J Biol Chem. 281:12751-12759. PDF
Kinlough CL, McMahan RJ, Poland PA, Bruns JB, Harkleroad KL, Stremple RJ, Kashlan OB, Weixel KM, Weisz OA, and Hughey RP (2006). MUC1 recycling is dependent on its palmitoylation. J Biol Chem. 281:12112-12122. PDF
Potter BA, Weixel KM, Bruns JR, Ihrke G, and Weisz OA (2006) N-glycans mediate apical recycling of the sialomucin endolyn in polarized MDCK cells. Traffic. 7:146-154 (highlighted by the Faculty of 1000). PDF
2005 – 2001
Chen C, Vincent O, Jin J, Weisz OA, and Montelaro RC (2005) Functions of early (AP-2) and late (AIP1/ALIX) endocytic proteins in equine infectious anemia virus budding. J Biol Chem. 280:40474-40480. PDF
Jin S, Zhang B, Weisz OA, and Montelaro RC (2005) Receptor-mediated entry by equine infectious anemia virus utilizes a pH-dependent endocytic pathway. J Virol. 79:14489-14497. PMCID: 1287590. PDF
Weixel KM, Blumental-Perry A, Watkins SC, Aridor M, and Weisz OA (2005) Distinct Golgi populations of phosphatidylinositol 4-phosphate regulated by phosphatidylinositol 4-kinases J Biol Chem. 280:10501-10508. PDF
Ellis MA, Miedel MT, Guerriero CJ, and Weisz OA (2004) ARF1-independent protein sorting and export from the trans-Golgi network. J Biol Chem. 279:52735-52743. PDF
Mohan S, Bruns JR, Weixel KM, Edinger RS, Bruns JB, Kleyman TR, Johnson JP, and Weisz OA (2004) Differential current decay profiles of ENaC subunit combinations in polarized renal epithelial cells. J Biol Chem. 279:32071-32078. PDF
Potter BA, Ihrke G, Bruns JR, Weixel KM, and Weisz OA (2004) Specific N-glycans direct apical delivery of transmembrane, but not soluble or GPI-anchored forms of endolyn in MDCK cells. Mol Biol Cell. 15:1407-1416 (highlighted by the Faculty of 1000). PMCID: 363156. PDF
Chen C, Weisz OA, Stolz DB, Watkins SC, and Montelaro RC (2004) Differential effects of actin cytoskeleton dynamics on equine infectious anemia virus particle production. J Virol. 78:882-891. PMCID: 368807. PDF
Puthenveedu M, Bruns JR, Weisz OA, and Linstedt, AD (2003) Basolateral cycling mediated by a lumenal domain targeting determinant. Mol Biol Cell. 14:1801-1807. PMCID: 165078.
Lee E, Marcucci M, Daniell L, Pypaert M, Weisz OA, Ochoa, G-C, Farsad, K, Wenk, MR, and De Camilli, P (2002) Amphiphysin 2 (Bin1) and T-tubule biogenesis in muscle. Science. 297:1193-1196 (highlighted by the Faculty of 1000). PDF
Bruns JR, Ellis MA, Jeromin A, and Weisz OA (2002) Multiple roles for phosphatidylinositol 4-kinase in biosynthetic transport in polarized MDCK cells. J Biol Chem. 277:2012-2018. PDF
Ihrke G, Bruns JR, Luzio JP, and Weisz OA. (2001) A novel lysosomal delivery route via the apical surface identified by the trafficking of endolyn in MDCK cells. EMBO J. 20:6256-6264. PMCID: 125743. PDF
2000 – 1997
Weisz OA, Wang J-M, Edinger RS, and Johnson JP (2000) Non-coordinate regulation of endogenous ENaC subunit expression at the apical membrane of A6 cells in response to various transporting conditions. J Biol Chem. 275:39886-39893.
Gibson GA, Hill WG, and Weisz OA (2000) Evidence against the acidification hypothesis in cystic fibrosis. Am J Physiol- Cell Physiol. 279:C1088-1099. PDF
Weisz OA, Gibson GA, Roder J, and Jeromin A (2000) Overexpression of frequenin, a modulator of phosphatidylinositol 4-kinase, inhibits biosynthetic delivery to the apical surface of polarized Madin-Darby canine kidney cells. J Biol Chem. 275:24341-24347.
Howard M, Jiang X, Beer Stolz D, Hill WG, Johnson JA, Watkins SC, Frizzell RA, Bruton CM, Robbins PD, and Weisz OA (2000) Forskolin-induced apical membrane insertion of virally-expressed, epitope-tagged CFTR in polarized MDCK cells. Am J Physiol- Cell Physiol. 279:C375-C382.
Henkel JR, Gibson GA, Poland PA, Ellis MA, Hughey RP, and Weisz OA (2000) Influenza M2 proton channel activity selectively inhibits TGN release of apical membrane and secreted proteins in polarized MDCK cells. J Cell Biol. 148:495-504 (highlighted in the In Brief section of Journal of Cell Biology 2000;148:1-2). PMCID: 2174804. PDF
Altschuler Y, Kinlough CL, Poland PA, Bruns JB, Apodaca G, Weisz OA, and Hughey RP (2000) Clathrin mediated endocytosis of MUC1 is modulated by its glycosylation state. Mol Biol Cell. 11:819-831. PMCID: 14813. PDF
Sevier CS, Weisz OA, Davis M, and Machamer CE (2000) Efficient export of the vesicular stomatitis virus glycoprotein from the endoplasmic reticulum requires a signal in the cytoplasmic tail that includes both tyrosine-based and di-acidic motifs. Mol Biol Cell. 11:13-22. PMCID: 14753.
Henkel JR, Popovich JL, Gibson GA, Watkins SC, and Weisz OA (1999) Selective perturbation of early endosome and/or TGN pH but not lysosome pH by dose-dependent expression of influenza M2 protein. J Biol Chem. 274:9854-9860. PDF
Rokaw MD, Wang J, Edinger RS, Weisz OA, Hui D, Middleton P, Shlyonsky V, Berdiev B K, Ismailov, I, Eaton DC, Benos DJ, and Johnson JP (1998) Carboxylmethylation of the beta subunit of xENaC regulates channel activity. J Biol Chem. 273:28746-28751.
Henkel JR, Apodaca G, Altschuler Y, Hardy S, and Weisz OA (1998) Selective perturbation of apical membrane traffic by expression of influenza M2, an acid-activated ion channel, in polarized Madin-Darby canine kidney cells. Mol Biol Cell. 9:2477-2490. PMCID: 25516. PDF
Henkel JR and Weisz OA (1998) Influenza virus M2 protein slows transport along the secretory pathway. J Biol Chem. 273:6518-6524. PDF
Jiang XS, Hill WG, Pilewski JM, and Weisz OA (1997) Glycosylation differences between a cystic fibrosis and rescued cell line are not CFTR-dependent. Am J Physiol- Lung Cell and Mol Physiol. 273:L913-L920.
Review Articles & Book Chapters
Shipman KE and Weisz OA (2020) Making a dent in Dent disease. Function. 2020;1(2):zqaa017. doi: 10.1093/function/zqaa017. PMID: 33015630; PMCID: PMC7519470. PDF
Weisz OA (2020) Targeting PIs to improve PTs: A new approach to treatment of genetic diseases of the proximal tubule. Kidney International. 98:824-826.
Labilloy A and Weisz OA (2019) Lose the Lipid: Renoprotection conferred by Gb3 synthase knockout. Kidney International. 96:270-272. PMID: 31331463
Baty CJ and Weisz OA (2018) Lemmings into the sea or back across the bridge? The fate of albumin in nephrotic syndrome. Kidney International. 93:296-298. PMID: 29389392
Eshbach ML and Weisz OA (2017) Receptor mediated endocytosis in the proximal tubule. Annu Rev Physiol. 79:425-448. PMID: 27813828; PMCID: PMC5512543.
Weisz OA and Fölsch H (2015) Molecular mechanisms of apical and basolateral sorting in polarized epithelial cells. Ion Channels and Transporters of Epithelia in Health and Disease, KL Hamilton and DC Devor, eds (Springer) Chapter 7, pp 279-302. PDF
Raghavan V and Weisz OA (2015) Discerning the role of mechanosensors in regulating proximal tubule function. Am J Physiol.310:F1-F5. PMID: 26662200; PMCID: PMC4675802 PDF
Raghavan V and Weisz OA (2015) Flow stimulated endocytosis in the proximal tubule. Curr Opin Nephrol Hypertens. 24:359-365. PMCID: PMC4494861 PDF
Little M, Brown D, Humphreys B, McMahon A, Miner JH, Sands JM, Weisz OA, Mullins C, and Hoshizaki D (2014) The critical value of defining kidney biology to understanding renal disease. Clin J Amer Soc Nephrol. 9:809-811. PDF
Weisz OA (2014) Protein Targeting. In: eLS 2014, John Wiley & Sons Ltd: Chichester http://www.els.net/ [DOI: 10.1002/9780470015902.a0005291.pub2].
Weisz OA (2013) High-tailing it to the apical surface: focus on “Apical targeting of the P2Y4 receptor is directed by hydrophobic and basic residues in the cytoplasmic tail”. Am J Physiol. 304:C226-227.
Welling, PA and Weisz OA (2010) Sorting it out in endosomes: An emerging concept in transport regulation. 25:280-292. PDF
Weisz OA and Rodriguez-Boulan E (2009) Apical trafficking in epithelial cells: signals, clusters and motors. J Cell Sci. 122:4253-4266.
Fölsch H, Mattila PE, and Weisz OA (2009) Taking the scenic route: Biosynthetic traffic to the plasma membrane in polarized epithelial cells. 10; 972-981. PDF
Butterworth MB, Weisz OA, and Johnson JP (2008) Some assembly required: putting the epithelial sodium channel together. J Biol Chem. 283:35305-35309. PDF
Ellis MA, Potter BA, Cresawn KO, and Weisz OA (2006) Polarized biosynthetic traffic in renal epithelial cells: sorting, sorting, everywhere. Am J Physiol. 291:F707-713. PDF
Potter BA, Hughey RP, and Weisz OA (2006) The role of N- and O-glycans in polarized biosynthetic sorting. Am J Physiol. 290:C1-10. PDF
Weisz OA and Johnson JP (2003) Non-coordinate regulation of ENaC: Paradigm lost? Am J Physiol. 285:F833-842.
Weisz OA (2003) Acidification and protein traffic. Int Rev Cytol. 226:259-319.
Weisz OA (2003) Organelle acidification and disease. 4:57-64.